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It is indicated in the prevention and treatment of iron deficiency anemia in pregnancy, nursing and menstruation, in cases of chronic or acute blood loss, dietary restriction, metabolic disease and post-surgical convalescence.
Adults: One capsule two times daily or as directed by the Healthcare Professionals.
Each capsule contains:
Ferrous Fumarate B.P ... 162 mg (equivalent to Iron 53.25 mg)
Folic Acid B.P ... 0.75 mg
Cyanocobalamin B.P (Vit B12) ... 7.5 mcg.
Ferrous Fumarate is an essential constituent of the body, being necessary for haemoglobin formation and for the oxidative process of living tissue.
Folic Acid is a substrate for an important reaction that involves vitamin B12. The pathway leading to the formation of tetrahydrofolate (THF) begins when folic acid (F) is reduced to dihydrofolate (DHF) which is then reduced to tetrahydrofolate (THF). Folic acid is necessary for the formation of a n...
Cyanocobalamin (Vitamin B12): Methylcobalamin and 5-deoxy-adenosyl-cobalamin are the active forms of cyanocobalamin which act as coenzymes in nucleic acid synthesis, control folate metabolism in haematopoiesis and maintain the functions of myelin sheath.
Ferrous Fumarate is mainly absorbed from duodenum and jejunum. Absorption is aided by the acid secretion of stomach. Absorption is also increased in iron deficiency or fasting state. Food and achlorhydria will decrease absorption. Its excretion is from urine, sweat, sloughing of intestinal mucosa an...
Folic acid is rapidly absorbed from the proximal part of small intestine and is distributed in body tissues. The naturally occurring folate polyglutamates are largely deconjugated and reduced prior to absorption. It is a 5 methyltetrahydrofolate which appears in the portal circulation, where it is e...
Once absorbed, cyanocobalamin is transported to the various cells of the body bound to a family of specialized glycoproteins, transcobalamin I, II, III. Excess B12 is stored in the liver.
It is contraindicated in patients who have known hyper-sensitivity to any of the components of this formulation; infants < 12 months: patients with hemochromatosis, hemosiderosis and non-iron deficiency anemia; history of nephrolithiasis; hyperoxaluria and oxalate dysbolism (risk of calculus) and th...
Use with caution in patients with gastrointestinal diseases eg, peptic ulcer, chronic ulcerative colitis and localized colitis.
Common side effects are constipation, diarrhea, nausea, vomiting, dark stools and stomachache. Usually, these side effects are transient.
Concurrent administration of 200 mg vitamin C per 30 mg elemental iron increases absorption of oral iron. Absorption of oral preparation of iron and tetracyclines are decreased when both of these drugs are given together. Absorption of fluoroquinolones, levodopa, methyldopa, and penicillamine may be...
Concurrent administration of antacids, H2 blockers (cimetidine), or proton pump inhibitors may decrease iron absorption. Response to iron therapy may be delayed by chloramphenicol.
Teas containing tannins eg, green tea and red tea may decrease iron absorption.
Store below 30°C in cool, dry place. Protect from light and moisture. Keep out of reach and sight of children.
10 x 10’s Blisters.